Just as smartphones can be improved through downloaded apps, the EHR can now be enhanced through interoperable apps developed by third-party innovators. Recognizing the promise of this approach early on, the University of Utah launched the ReImagine EHR initiative in 2016 to develop EHR-integrated apps that leverage interoperability standards including FHIR and SMART. Supportive infrastructure developed include various FHIR-related tooling and a systematic evaluation framework known as ELICIT. More than 10 EHR-integrated digital innovations have been implemented, and initial evaluations have demonstrated positive impact on patients and providers. Return on invstment has included improvements in care; over $35 million in grant funding; commercial opportunities; and increased ability to adapt to a changing healthcare landscape. In this panel, leaders of the initiative will describe their journey and the lessons learned, with the hopes of helping others join them in the quest to improve patient lives through digital health innovation.