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With the advancement of digital technologies, patients can easily collect their own health data outside of the clinical setting to track and manage their health. While these technologies are promising, many ambulatory care practices lack the technical infrastructure, functional workflows, workforce capacity, and training to support the intake and use of patient-generated health data (PGHD). This panel will feature opportunities and recommendations regarding PGHD integration in ambulatory care settings. Specifically, the panel will feature findings from a recent environmental scan and guidance from a practical guide as well as examples from two health systems that use different technical approaches to collect and integrate PGHD with electronic health records. The learning objectives include: (1) understanding the current state and recommendations of PGHD integration, and (2) learning different technical architectures and workflows that support the collection and integration of standardized PGHD either self-reported by patients or directly from devices.