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Keeping up with the literature in biomedical and health informatics is an essential professional endeavor – but one that is daunting, given the exponential proliferation of peer-reviewed publications in the field. We can help by providing a sampler of papers that AMIA Working Groups find significant. Presented in rapid fire, entertaining style, the AMIA "Informatics Year in Review" session at the Annual Symposium is consistently one of the most highly attended sessions on the agenda and one that attendees find a valuable supplement to their own readings.